Research

In my research, I use computer simulations to study the phase behavior and dynamics of many-body systems. Broadly, my research interests can be divided up into two main categories: the structure and dynamics of bond-forming liquids, and the self-assembly of colloidal particles.

Below are some past research highlights.


Structure in glassy fluids

Tetrahedrality dictates dynamics in hard spheres

Within the same theme of linking local structure to glassy dynamics, here we explore the correlation between structure and glassy dynamics in a wide range of binary hard-sphere mixture with different size ratios, compositions, and packing fractions. Instead of focusing on icosahedra, we focus on the most fundamental local cluster possible in 3D: the tetrahedron. With its mechanical stability and efficient packing, the simple tetrahedron can be seen as the most fundamental local structure in a disordered fluid. Intriguingly, we find that the global diffusivity of a large range of hard-sphere mixtures can be predicted based only on the number of tetrahedral clusters per particle, with high tetrahedrality corresponding to slow dynamics. Moreover, local tetrahedrality provides an excellent predictor for future local dynamics, indicating that these structures indeed play a key role in slowing down rearrangements. As tetrahedra are also the key building block for many local structures previously linked to slow dynamics (including the icosahedron), this simple cluster may be the key to understanding glassy dynamics in a wide range of systems.
The figure shows a snapshot of a glassy systems with particles colored either by tetrahedrality (top, red corresponds to low tetrahedrality) or mobility (bottom, red corresponds to high mobility).
In collaboration with S. Marín Aguilar, H. H. Wensink, and G. Foffi.
Accepted in Phys. Rev. Lett., link to arxiv: arXiv

Designing slower glasses by manipulating their local structure

Recent research on a variety of glass formers has demonstrated that local structural ordering plays a key role in the dynamics of glassy liquids. In particular, the local packing of particles defines the cages which particles need to escape in order for the system to relax its structure. Here, we use this observation to tune the glassy dynamics of a model glass former using short-range directional (``patchy'') interactions. Starting from a dense binary-hard sphere mixture, we use computer simulations to explore the glassy dynamics of patchy particles with a wide range of geometries. We find that out of all geometries, particles with icosahedral symmetry are uniquely capable of facilitating dynamical arrest. In contrast, this slowdown is absent for the other investigated patch geometries. Hence, the slowest liquids are those where the particles enhance the number of icosahedral cages in the system. These cages are uniquely stable structures, which drastically impact the relaxation rate of the system. As icosahedral structures are also known to suppress the formation of long-ranged crystals, boosting their prevalence in a supercooled liquid is likely to lead to an excellent glass former. Our results highlight the special role of icosahedral caging in glassy liquids, and provide a way to control the dynamics of dense systems by selectively promoting specific local structural environments.
In collaboration with S. Marín Aguilar, H. H. Wensink, and G. Foffi.
Link to paper: arXiv

Bond-forming liquids

Some of the most intriguing phase behavior is found in particles which can only form a limited number of attractive bonds with their neighbors. An excellent example of this is water: under typical conditions, a water molecule can form up to four hydrogen bonds to nearby other molecules. The limitation on the number of bonds gives rise to a network-like liquid phase, open crystal structures, and a variety of anomalous features in the phase behavior and dynamics of water. Similar structures can be found in a variety of atomic and molecular systems (such as silicon and silica), colloidal particles with attractive patches, and polymer networks. In this line of research, I use simulations on both simplified and realistic models to identify and understand the physics governing the behavior of this intriguing class of systems.

Erasing no-man's land by thermodynamically stabilizing the liquid-liquid transition in tetrahedral particles

One of the more controversial topics in the study of water and other tetrahedrally coordinated liquids is the existence of a liquid-liquid phase transition. In this scenario, the liquid phase separates into a low-density and high-density liquid when cooled below the liquid-liquid critical temperature. Unfortunately, if such a transition exists, this critical temperature is far below the freezing temperature, and as a result, both experimental and computational tests of this hypothesis are plagued by rapid crystallization. In order to circumvent this problem, we designed a patchy particle model for tetrahedral liquids where the flexibility and length of the interparticle bonds can be independently controlled. Using extensive free-energy calculations, we show that a liquid-liquid phase transition is not only present in our model, but also that it can be completely stabilized with respect to crystallization by tuning the bond flexibility. As a result, the model provides a recipe for designing colloidal analogues of tetrahedral liquids that exhibit a liquid-liquid critical point.
The picture shows a spontaneously formed liquid-liquid phase coexistence. The colors of the particles indicate the local density: red is high, green is low.
In collaboration with L. Filion and F. Sciortino.
Link to paper: Nat. Phys.
Commentary by Francis Starr: Nat. Phys.

Tuning the liquid-liquid transition by modulating the hydrogen bond angular flexibility in a model for water

In a follow-up to the work above, we extended the concept of bond flexibility to a more realistic model for water known as the ST2 model. Although a liquid-liquid phase transition has been reported in ST2, it has been a matter of some debate whether this observation could be an artifact resulting from crystallization. In the ST2 model, each water molecule is considered as a rigid cluster of four point charges (two positive and two negative), around a central core. The molecules can form a tetrahedral network similar to those formed by the patchy particle systems we studied earlier. By allowing the charges within each molecule to fluctuate, we can increase the bond flexibility of this model. We show that, as in the case of the patchy-particle model, increasing the flexibility results in a full stabilization of the liquid-liquid transition with respect to the low-density (diamond) crystal structure, such that nucleation of this structure is no longer a concern. Our results provide additional evidence for the presence of a true liquid-liquid critical point in ST2, and emphasize again that bond flexibility is a key parameter for determining the existence of a secondary liquid phase in tetrahedral liquids.
The picture shows a schematic representation of the ST2 model with added flexibility.
In collaboration with F. Sciortino.
Link to paper: Phys. Rev. Lett., arXiv

Liquids more stable than crystals in particles with limited valence and flexible bonds

Patchy particles with four tetrahedrally arranged patches are known to form a low-density diamond crystal phase at low temperatures, but this phase becomes less stable as the size of the patches (or bond flexibility) increases. We investigated the effect of patch width on the phase behavior of patchy particles modeled via the Kern-Frenkel model, with the additional limitation that each patch can form at most a single bond. This limitation allows us to examine particles with highly flexible bonds that nevertheless maintain a limited valence. In these systems, the low-density crystal phase vanishes from the phase diagram, and is replaced by a region where the liquid phase is stable even in the low-temperature limit. This almost fully bonded liquid is stabilized by the configurational entropy associated with the number of ways the network can be bonded. Additionally, we show that the diffusion in the liquid is dominated by the hopping of broken bonds.
The picture shows the particles (left) and bonds (right, connecting the centers of bonded particles) in a fully bonded disordered network.
In collaboration with F. Sciortino.
Link to paper: Nat. Phys., arXiv
Commentary by Jeppe Dyre: Nat. Phys.

Patchy particle model for vitrimers

Vitrimers are a recently invented class of polymers with highly useful material properties. They are covalently bonded networks, consisting of (typically) two types of monomers, each with a limited functionality (or valence). The bonds can rearrange, and thus relax the network topology, via catalyst-aided bond exchange reactions. Since only bonds between monomers of different species are allowed, and the covalent bonds are too strong to break, the total number of bonds in the system is essentially fixed by the composition. Using a variation on our wide-patch Kern-Frenkel model (see above), we demonstrate a patchy-particle model for vitrimers that mimicks the unique bond-switching mechanic of vitrimers. We calculate the phase diagram of the model using both simulations and a simple, parameter-free thermodynamic perturbation theory, and show that vitrimers are expected to phase separate at low densities into a highly bonded network phase and a dilute gas phase. Additionally, we investigate the viscosity in our model system, and show that the model exhibits the same strong (silica-like) glass-forming behavior that is observed in vitrimers.
The picture shows the particles (left) and bonds (right) in part of a vitrimer network. The different colors indicate different monomer species: 4-patch (blue) and 2-patch (red) particles.
In collaboration with L. Leibler and F. Sciortino.
Link to paper: Phys. Rev. Lett.


Colloidal self-assembly

Under the right conditions, colloidal particles suspended in a solvent can self-assemble into intricate structures, including crystals, liquid crystals, finite clusters, or networks. These structures are determined mainly by the interactions between the particles. In this line of research, I investigate the self-assembly of a wide range of model colloidal systems, either by directly simulating the self-assembly process, or by performing free-energy calculations on competing phases to determine their relative stability.

Close packing of rods on spherical surfaces

The best way to pack spheres or rods densely in a flat plane is on a simple periodic lattice. However, the best packing of particles on a spherical surface is much less clear, and strongly dependent on the ratios between the rod length, the rod diameter, and the radius of the spherical surface. Using numerical optimization techniques, we explored the best packed structures for short rods on spherical surfaces, and found a rich variety of cluster symmetries. Intriguingly, very short rods both come closer to their maximum packing and form fewer defects than both spheres and longer rods, assuming clusters of similar size. Our results could guide the design of colloidosomes -- hollow shells of colloidal particles self-assembled on the surface of e.g. emulsion droplets -- with new symmetries and pore size distributions.
The picture shows a highly symmetric close-packed cluster of 42 rods.
In collaboration with H. Löwen
Link to paper: arXiv

Vacancy-stabilized crystalline order in hard cubes

At first glance, hard cubes seem to be a simple system, but its (simple cubic) crystalline phase shows some surprising properties. Using free energy calculations, we showed that close to the melting point, the equilibrium crystal phase shows a surprisingly high concentration of vacancies: while the particles are on average placed on a crystal lattice, there can be up to 6% fewer particles than lattice sites in the system. Moreover, the vacancies are delocalized; they are spread out over multiple lattice sites, increasing the freedom of movement for several nearby particles. In event-driven molecular dynamics simulations, these vacancies can be shown to be highly mobile, leading to a highly diffusive crystal phase. The picture is a snapshot of a typical crystalline configuration, where the vacancies and the particles which surround the vacancy have been highlighted (yellow).
In collaboration with L. Filion, M. Marechal, and M. Dijkstra.
Link to paper: PNAS, arXiv
Commentary by Daan Frenkel: PNAS
Highlighted in the Journal Club for Condensed Matter Physics: 1 2

Phase diagram of colloidal spheres in a biaxial electric or magnetic field

Colloidal particles with a dielectric constant mismatch with the surrounding solvent in an external biaxial magnetic or electric field experience an ``inverted'' dipolar interaction, where particles attract in the plane of the external field, and repel in the direction perpendicular to it, resulting in sheet-like structures. We determine the phase behavior of hard spheres in such a field, using Helmholtz free energy calculations and Monte Carlo simulations, both with and without an additional screened-charge repulsion. Without charges, the phase diagram shows a gas-liquid transition, a hexagonal ABC stacked crystal phase, and a stretched hexagonal-close-packed crystal. The phase diagram for charged spheres is very similar, but displays an additional layered-fluid phase. We compare our results with recent experimental observations.
The picture shows different phases in the charged system: (a) gas, (b) liquid (c) layered fluid, (d) crystal.
In collaboration with M. Dijkstra.
Link to paper: J. Chem. Phys.